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Severe allergic reactionsanaphylaxisare exceptionally rare, occurring in fewer than 0.1% of cases

As with most treatments, there are some mild side effects

While real-world Tirzepatide dose escalations were slower than those observed during the drug's clinical trials, with many patients remaining on lower doses such as 5 mg or 7.5 mg even after six months due to factors like off-label prescribing practices, supply constraints, or provider and patient preferences, patients who persisted with the medication for at least 6 months witnessed a mean weight reduction of 12.9% among a subset of persistent, GLP-1 naive patients, not the entire cohort compared to baseline values

A previous systematic review also reported that administration of AOXs such as vitamin E, vitamin C, N-acetyl cysteine (NAC), carnitines, CoQ10, lycopene, selenium, and zinc, resulted in significant improvement of sperm concentration, motility, and morphology (102)